Protein Modification Reagents
Medchemexpress LLC Bis-PEG4-NHS ester | 1g
Bis- PEG4- NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC)
Medchemexpress LLC Azido-PEG5-CH2CO2H | 217180-81-9 | MFCD31561141 | 98.9% | 321.33 g/mol | C12H23N3O7 | 25 MG
Azido-PEG5-CH2CO2H is an azide-functional polyethylene glycol (PEG) linker containing five ethylene glycol units, used as a cleavable spacer for bioconjugation. It is commonly applied in antibody-drug conjugate and PROTAC linker synthesis, and as a reagent for click chemistry (CuAAC and SPAAC).
- Azide-functional group for click chemistry (CuAAC and SPAAC).
- Five-unit PEG spacer provides hydrophilicity and flexibility.
- Cleavable carboxylic acid terminus suitable for conjugation strategies.
- High reported purity (~98.9%).
- Molecular weight ~321.33 g/mol; formula C12H23N3O7.
- Available in small research quantities (e.g., 25 mg).
Broadpharm t-Boc-N-amido-PEG2-acid | 1365655-91-9 | MFCD22056304 | 500 mg
t-Boc-N-amido-PEG2-acid | Purity: 98% | Mol Wt: 277.3 | 1365655-91-9 | MFCD22056304 | 500 mg
eMolecules 1334177-86-4 | Mal-amido-PEG8-acid | MakeChem, Inc. | MFCD13184956 | 592.639 | C26H44N2O13 | 0.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O | 1g | 859841979
Mal-amido-PEG8-acid | MakeChem, Inc. | 1334177-86-4 | MFCD13184956 | 592.639 | C26H44N2O13 | 0.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O | 1g | 859841979
Medchemexpress LLC 3,6,9,12-tetraoxatridecan-1-amine | 85030-56-4 | MFCD11041099 | 98.8% | 207.27 g/mol | C9H21NO4 | 500 MG
m-PEG4-Amine is a short polyethylene glycol (PEG4) amine reagent used as a linker in chemical biology applications. It is commonly used in the synthesis of proteolysis targeting chimeras (PROTACs) and can serve as a cleavable linker in antibody-drug conjugate (ADC) construction. The reagent is supplied at research-grade purity for laboratory use.
- Short PEG4 amine linker for conjugation chemistry.
- Useful for PROTAC design and linker optimization.
- Functions as a cleavable linker for ADC synthesis.
- High purity suitable for research applications.
- Molecular weight 207.27 g/mol; formula C9H21NO4.
Medchemexpress LLC Mal-amido-PEG6-NHS ester | 1137109-21-7 | 98.8% | 601.60 | 500 MG
Mal-amido-PEG6-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Dspe-peg-fluor 647 | 95.4% | 5000 | 1 MG
DSPE-PEG-Fluor 647, MW 5000 is a PEGylated lipid with a DSPE group and a Fluor 647 fluorophore. DSPE is a phospholipid. Fluor 594 is a red water-soluble dye.
- Pegylated lipid
- Contains DSPE group and a Fluor 647 fluorophore
- DSPE is a phospholipid
- Fluor 594 is a red water-soluble dye
Medchemexpress LLC Tetraglyme | 143-24-8 | 99.93% | 222.28 | 500 G
Me-PEG4-Me is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is for an E3 ubiquitin ligase and the other for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Is a peg-based protac linker
- Useful in the synthesis of protacs
STA PHARMACEUTICAL US LLC Azide-PEG3-L-alanine-Fmoc | 100 g | CAS 2054345-69-4 | InChIKey YTHKPQSMRZQREU-JOCHJYFZSA-N
Azide-PEG3-L-alanine-Fmoc is a Amino Acid reagent (Subcategory: Azido/Alkynyl AA) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 2054345-69-4
- MDL: No data
- InChIKey: YTHKPQSMRZQREU-JOCHJYFZSA-N
- Molecular Weight: 484.509
- Molecular Formula: C24H28N4O7
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29299090
- Country Of Origin: China
- IUPAC: N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(2-(2-(2-azidoethoxy)ethoxy)ethyl)-D-serine
- SMILES: O=C(N[C@H](COCCOCCOCCN=[N+]=[N-])C(O)=O)OCC1C2=C(C=CC=C2)C3=C1C=CC=C3
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG5-CH2COOH | 5 g | CAS 635287-26-2 | InChIKey LNIFRTLAPAPKAG-UHFFFAOYSA-N
Fmoc-NH-PEG5-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 635287-26-2
- MDL: No data
- InChIKey: LNIFRTLAPAPKAG-UHFFFAOYSA-N
- Molecular Weight: 517.575
- Molecular Formula: C27H35NO9
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azahenicosan-21-oic acid
- SMILES: O=C(COCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Medchemexpress LLC Mal-amido-PEG2-C2-acid | 756525-98-1 | 99.8% | 328.32 | 1 G
Mal-amido-PEG2-C2-acid is a PROTAC linker that is PEG-based and can be utilized in the synthesis of PROTACs. PROTACs themselves consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a protein of interest. PROTACs function by leveraging the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is intended for research use only and is not sold to patients.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
eMolecules 1807518-63-3 | BROMO-PEG2-CH2CO2TBU | AstaTech | MFCD28122957 | 283.162 | C10H19BrO4 | 95.000 | CC(C)(C)OC(=O)COCCOCCBr | 1g | 487923071
BROMO-PEG2-CH2CO2TBU | AstaTech | 1807518-63-3 | MFCD28122957 | 283.162 | C10H19BrO4 | 95.000 | CC(C)(C)OC(=O)COCCOCCBr | 1g | 487923071